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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
4.24
Human Site:
S506
Identified Species:
7.18
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
S506
S
P
R
G
Q
K
A
S
P
P
T
L
A
P
A
Chimpanzee
Pan troglodytes
XP_509441
819
90122
A476
V
L
K
N
A
R
I
A
P
A
A
F
S
G
Q
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
E69
L
P
R
R
R
D
Q
E
G
S
V
G
P
S
D
Dog
Lupus familis
XP_546925
857
93734
S511
S
P
R
G
R
K
P
S
P
P
T
L
A
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
L518
Q
K
A
S
P
P
T
L
A
S
A
T
A
S
P
Rat
Rattus norvegicus
Q6AXT8
471
49872
R150
E
G
V
M
P
R
H
R
F
M
S
A
Y
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
P550
K
A
K
R
L
P
G
P
P
V
P
S
H
L
T
Frog
Xenopus laevis
NP_001084764
548
60887
R227
W
K
S
I
V
D
G
R
D
T
P
V
P
M
E
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
L481
S
Q
P
V
N
F
A
L
P
K
S
I
Q
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
Q485
C
S
N
L
L
V
T
Q
Q
M
Q
Q
A
T
S
Honey Bee
Apis mellifera
XP_394429
1014
115124
N667
L
L
A
Q
L
L
T
N
N
T
S
G
I
H
T
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
P568
N
Q
T
G
P
Q
T
P
L
G
Q
L
I
G
S
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
P968
P
P
A
P
E
P
A
P
V
M
V
M
A
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
A738
P
P
P
P
P
P
P
A
P
P
T
P
Q
S
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
6.6
13.3
86.6
N.A.
6.6
0
N.A.
N.A.
6.6
0
26.6
N.A.
6.6
0
13.3
20
P-Site Similarity:
100
33.3
20
93.3
N.A.
6.6
13.3
N.A.
N.A.
13.3
6.6
40
N.A.
13.3
13.3
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
22
0
8
0
22
15
8
8
15
8
36
0
15
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
15
0
0
8
0
0
0
0
0
8
% D
% Glu:
8
0
0
0
8
0
0
8
0
0
0
0
0
8
8
% E
% Phe:
0
0
0
0
0
8
0
0
8
0
0
8
0
0
0
% F
% Gly:
0
8
0
22
0
0
15
0
8
8
0
15
0
15
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
8
8
0
% H
% Ile:
0
0
0
8
0
0
8
0
0
0
0
8
15
0
0
% I
% Lys:
8
15
15
0
0
15
0
0
0
8
0
0
0
8
0
% K
% Leu:
15
15
0
8
22
8
0
15
8
0
0
22
0
8
0
% L
% Met:
0
0
0
8
0
0
0
0
0
22
0
8
0
8
0
% M
% Asn:
8
0
8
8
8
0
0
8
8
0
0
0
0
0
8
% N
% Pro:
15
36
15
15
29
29
15
22
43
22
15
8
15
22
15
% P
% Gln:
8
15
0
8
8
8
8
8
8
0
15
8
15
0
15
% Q
% Arg:
0
0
22
15
15
15
0
15
0
0
0
0
0
0
0
% R
% Ser:
22
8
8
8
0
0
0
15
0
15
22
8
8
22
22
% S
% Thr:
0
0
8
0
0
0
29
0
0
15
22
8
0
8
15
% T
% Val:
8
0
8
8
8
8
0
0
8
8
15
8
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _